THE MEMBRANE ELECTRICAL POTENTIAL AND INTRACELLULAR PH AS FACTORS INFLUENCING INTRACELLULAR ASCORBATE CONCENTRATION AND THEIR ROLE IN CANCER TREATMENT

Ascorbate is an important element of a variety of cellular processes including the control of reactive oxygen species levels.Since reactive oxygen Toothbrushes species are implicated as a key factor in tumorigenesis and antitumor therapy, the injection of a large amount of ascorbate is considered beneficial in cancer therapy.Recent studies have sho

Summary: This protocol allows repeated whole-cell patch-clamp recordings from individual rodent CA1 hippocampal neurons, followed by immunohistological Refrigerated Prep Tables labeling of the axon initial segment.This overcomes the need to maintain whole-cell recordings over the timescales required for homeostatic modification to cellular excitabi

Divya Vanoh,1 Suzana Shahar,2 Hanis Mastura Yahya,2 Normah Che Din,2 Arimi Fitri Mat Ludin,2 Devinder Kaur Ajit Singh,2 Razinah Sharif,2 Nor Fadilah Rajab2 1Nutrition & Dietetics Programme, School of Health Science, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia; 2Center for Healthy Aging and Wellness (H‐Care), Fa

Propellers for electric aviation are used in solo- Salt Mill and multirotor applications.Multifidelity analysis with reduced cycle time is crucial to explore several designs for energy minimization and range maximization.A low-fidelity design tool, py_BEM, is developed for design and analysis of a reverse-engineered solo 2-bladed propeller using bl

This study was designed to identify an immune-related gene signature (IRGS) associated with breast cancer (BC) patient outcomes.Transcriptomic data from 1411 BC patients in the TCGA and GEO databases were used to identify differentially expressed immune-related genes (DEIGs) when comparing BC tumor and normal tissue samples.We were able to construc